close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pef1Penta-EF-hand domain containing 1. (285 aa)    
Predicted Functional Partners:
pdcd6ip
Programmed cell death 6 interacting protein.
    
 
 0.808
W5K202_ASTMX
SEC31 homolog A, COPII coat complex component.
    
 
 0.733
LOC103026503
SEC31 homolog B, COPII coat complex component.
    
 
 0.722
fam83b
Family with sequence similarity 83 member B.
      
 0.658
TINAGL1
Tubulointerstitial nephritis antigen like 1; Belongs to the peptidase C1 family.
      
 0.655
Gfral
GDNF family receptor alpha like.
      
 0.621
ENSAMXP00000054535
Uncharacterized protein.
   
 0.596
LOC103041267
Heme-binding protein soul5.
    
   0.592
ENSAMXP00000054530
Heme binding protein 2.
    
   0.592
LOC103023878
Heme-binding protein soul5, like.
    
   0.558
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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