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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tnfaip6Tumor necrosis factor, alpha-induced protein 6. (264 aa)    
Predicted Functional Partners:
LOC103041992
Pentraxin 3, long b.
   
 
 0.798
ptx3
Pentraxin 3, long a.
   
 
 0.798
LOC111191160
CD44 molecule (Indian blood group) a.
     
0.745
Cd44
Link domain-containing protein.
     
 0.745
LOC111194997
Interleukin-1.
   
 0.596
ENSAMXP00000046425
Interleukin-1.
   
 0.596
LOC103041009
Tumor necrosis factor b (TNF superfamily, member 2).
   
 
 0.591
LOC111191478
Betacellulin, epidermal growth factor family member.
      
 0.579
fnta
Farnesyltransferase, CAAX box, alpha.
      
 0.578
W5KPB4_ASTMX
Uncharacterized protein.
   
  
 0.573
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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