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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KUR6_ASTMXPolycystic kidney disease 1a. (4355 aa)    
Predicted Functional Partners:
pkd2
Polycystic kidney disease 2.
    
0.936
LOC103031316
Polycystic kidney disease 2-like 1.
    
0.935
ENSAMXP00000038861
Myotilin.
    
 0.844
nphp1
Nephronophthisis 1.
   
 
 0.639
Exoc4
Exocyst complex component 4.
     
 0.633
exoc8
Exocyst complex component 8.
     
 0.609
exoc1
Exocyst complex component 1.
     
 0.608
W5KTH2_ASTMX
TSC complex subunit 2.
   
  
 0.602
rtf2
Replication termination factor 2.
   
  
 0.595
trpc1
Transient receptor potential cation channel, subfamily C, member 1; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.587
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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