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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Unc45bUnc-45 myosin chaperone B. (917 aa)    
Predicted Functional Partners:
LOC103024139
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.
   
 
 0.751
hsp90ab1
Heat shock protein 90, alpha (cytosolic), class B member 1.
   
 
 0.739
LOC103044252
SET and MYND domain containing 1b.
   
  
 0.699
W5KMM6_ASTMX
TSC complex subunit 1b.
   
 
 0.656
tsc1
TSC complex subunit 1a.
   
 
 0.656
trap1
TNF receptor-associated protein 1.
   
 
 0.656
W5LB00_ASTMX
Myosin IF; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.624
W5LQQ3_ASTMX
Myosin IEb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.624
LOC103047085
Myosin IEa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.624
Hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 
 0.620
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.