STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KUV6_ASTMXRho guanine nucleotide exchange factor (GEF) 33. (659 aa)    
Predicted Functional Partners:
ENSAMXP00000036302
Rho guanine nucleotide exchange factor (GEF) 38.
   
 
 0.799
LOC103031415
Rho guanine nucleotide exchange factor (GEF) 40.
     
 0.681
sting1
Transmembrane protein 173.
   
 0.671
Plekhg7
Pleckstrin homology domain containing, family G (with RhoGef domain) member 7.
    
 0.661
ENSAMXP00000048575
Uncharacterized protein.
    
 0.661
uchl5
Ubiquitin carboxyl-terminal hydrolase.
      
 0.535
W5KV20_ASTMX
Kalirin RhoGEF kinase a.
     
 0.533
W5LFE7_ASTMX
Tumor protein p53 binding protein, 1.
    
 0.521
arhgef2
Rho/rac guanine nucleotide exchange factor (GEF) 2.
    
 0.517
afmid
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
   
  
 0.517
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.