close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103024106Actinin, alpha 2b. (896 aa)    
Predicted Functional Partners:
LOC103022703
Myosin, light chain 1, alkali; skeletal, fast.
   
 0.725
ENSAMXP00000028251
Troponin T type 2b (cardiac).
   
 0.665
myoz1
Myozenin 1a.
   
 
 0.644
LOC103038989
Vinculin a.
   
 
 0.641
LOC103035083
Vinculin b.
   
 
 0.641
capzb
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 0.635
W5L1R1_ASTMX
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
   
  0.586
Cask
Calcium/calmodulin-dependent serine protein kinase a; Belongs to the MAGUK family.
   
  0.586
LOC103040917
Uncharacterized protein; Belongs to the tropomyosin family.
   
 0.581
tpm1
Uncharacterized protein; Belongs to the tropomyosin family.
   
 0.581
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (34%) [HD]