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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103039285Kelch-like family member 4. (719 aa)    
Predicted Functional Partners:
W5KX87_ASTMX
Cullin 3a; Belongs to the cullin family.
    
 0.774
cul3
Cullin 3b; Belongs to the cullin family.
    
 0.774
Rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.749
W5KW74_ASTMX
Sequestosome 1.
    
 0.736
bbs1
Bardet-Biedl syndrome 1.
    
 0.711
bbs9
Bardet-Biedl syndrome 9.
    
 0.684
bbs4
Bardet-Biedl syndrome 4.
    
 0.676
ttc8
Tetratricopeptide repeat domain 8.
    
 0.642
bbs7
Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.
   
 0.637
UBB
Ubiquitin B.
    
 0.585
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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