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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ntrk2Tyrosine-protein kinase receptor. (796 aa)    
Predicted Functional Partners:
LOC103030601
Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.
    
 0.928
bdnf
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
   
 0.904
ngf
Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family.
     
 0.806
LOC103046713
Growth factor receptor-bound protein 2a.
    
 0.798
LOC111191028
Growth factor receptor-bound protein 2b.
    
 0.798
efna5
Ephrin-A5b; Belongs to the ephrin family.
    
 0.753
LOC103028810
Ephrin-A5a; Belongs to the ephrin family.
    
 0.753
kitlg
Kit ligand a.
     
 0.752
LOC103024122
Insulin-like growth factor 2b.
    
 0.747
Ins
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.746
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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