Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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c6h9orf64Queuosine salvage protein; Involved in salvaging queuosine. (339 aa)    
Predicted Functional Partners:
qtrt1
Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...]
 
   
 0.741
qtrt2
Queuine tRNA-ribosyltransferase accessory subunit 2.
     
 0.692
W5JYN8_ASTMX
Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
   
    0.674
ciao2a
Cytosolic iron-sulfur assembly component 2A.
      
 0.637
poll
Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family.
    
   0.610
rnf181
Ring finger protein 181.
      
 0.490
LOC103028884
Chloride intracellular channel protein; Belongs to the chloride channel CLIC family.
      
 0.488
prdx4
Peroxiredoxin 4.
   
    0.458
prim1
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
    0.445
marveld1
MARVEL domain containing 1.
      
 0.427
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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