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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KVQ4_ASTMXRegulator of G protein signaling 12a. (1340 aa)    
Predicted Functional Partners:
apc2
APC regulator of WNT signaling pathway 2.
   
 0.574
Apc
APC regulator of WNT signaling pathway.
   
 0.574
csnk1a1
Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.
    
 0.527
W5KP23_ASTMX
Regulator of G protein signaling 3a.
   
 
0.521
LOC103021936
Regulator of G protein signaling 3b.
   
 
0.521
LOC103037569
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1.
   
 0.512
ENSAMXP00000052466
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2.
   
 0.512
gsk3b
Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily.
    
 0.500
gsk3a
Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.
    
 0.500
LOC103043574
Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.
    
 0.500
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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