| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FADS6 | LOC103021835 | ENSAMXP00000004330 | ENSAMXP00000039852 | Fatty acid desaturase 6. | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | 0.733 |
| FADS6 | Sdha | ENSAMXP00000004330 | ENSAMXP00000046972 | Fatty acid desaturase 6. | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.559 |
| FADS6 | W5KVH9_ASTMX | ENSAMXP00000004330 | ENSAMXP00000011591 | Fatty acid desaturase 6. | Cytochrome P450, family 11, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. | 0.733 |
| FADS6 | W5KVQ8_ASTMX | ENSAMXP00000004330 | ENSAMXP00000011670 | Fatty acid desaturase 6. | 2Fe-2S ferredoxin-type domain-containing protein. | 0.937 |
| FADS6 | iscu | ENSAMXP00000004330 | ENSAMXP00000040287 | Fatty acid desaturase 6. | Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.675 |
| FADS6 | ndufs2 | ENSAMXP00000004330 | ENSAMXP00000046260 | Fatty acid desaturase 6. | NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. | 0.627 |
| FADS6 | nfs1 | ENSAMXP00000004330 | ENSAMXP00000036095 | Fatty acid desaturase 6. | NFS1 cysteine desulfurase. | 0.712 |
| FADS6 | scly | ENSAMXP00000004330 | ENSAMXP00000029948 | Fatty acid desaturase 6. | Selenocysteine lyase. | 0.577 |
| LOC103021835 | FADS6 | ENSAMXP00000039852 | ENSAMXP00000004330 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Fatty acid desaturase 6. | 0.733 |
| LOC103021835 | LOC103022783 | ENSAMXP00000039852 | ENSAMXP00000016702 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Zgc:92275. | 0.455 |
| LOC103021835 | W5KVQ8_ASTMX | ENSAMXP00000039852 | ENSAMXP00000011670 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | 2Fe-2S ferredoxin-type domain-containing protein. | 0.810 |
| LOC103022783 | LOC103021835 | ENSAMXP00000016702 | ENSAMXP00000039852 | Zgc:92275. | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | 0.455 |
| LOC103022783 | Sdha | ENSAMXP00000016702 | ENSAMXP00000046972 | Zgc:92275. | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.924 |
| LOC103022783 | W5KVH9_ASTMX | ENSAMXP00000016702 | ENSAMXP00000011591 | Zgc:92275. | Cytochrome P450, family 11, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. | 0.455 |
| LOC103022783 | W5KVQ8_ASTMX | ENSAMXP00000016702 | ENSAMXP00000011670 | Zgc:92275. | 2Fe-2S ferredoxin-type domain-containing protein. | 0.829 |
| Sdha | FADS6 | ENSAMXP00000046972 | ENSAMXP00000004330 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | Fatty acid desaturase 6. | 0.559 |
| Sdha | LOC103022783 | ENSAMXP00000046972 | ENSAMXP00000016702 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | Zgc:92275. | 0.924 |
| Sdha | W5KVQ8_ASTMX | ENSAMXP00000046972 | ENSAMXP00000011670 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 2Fe-2S ferredoxin-type domain-containing protein. | 0.793 |
| Sdha | iscu | ENSAMXP00000046972 | ENSAMXP00000040287 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.541 |
| Sdha | ndufs2 | ENSAMXP00000046972 | ENSAMXP00000046260 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. | 0.996 |