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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103028648Protein disulfide-isomerase. (494 aa)    
Predicted Functional Partners:
tapbp
TAP binding protein (tapasin), tandem duplicate 1.
    
 0.966
LOC103024869
Calreticulin.
   
 0.952
LOC103040817
Calreticulin.
   
 0.949
LOC103036712
Transporter associated with antigen processing, subunit type t, teleost specific.
   
  0.921
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
  
 0.907
pdia3
Protein disulfide-isomerase.
  
  
 
0.901
LOC103024123
Protein disulfide-isomerase.
  
  
 
0.901
ero1b
Endoplasmic reticulum oxidoreductase beta.
   
 0.784
ero1a
Endoplasmic reticulum oxidoreductase alpha.
   
 0.784
W5LQI6_ASTMX
Calreticulin.
   
 0.759
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.