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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
parlRhomboid domain-containing protein. (392 aa)    
Predicted Functional Partners:
stoml2
Stomatin (EPB72)-like 2.
   
 0.706
yme1l1
YME1-like 1b.
   
 
 0.674
LOC103045642
YME1-like 1a.
   
 
 0.674
pink1
PTEN induced kinase 1.
    
 
 0.624
LOC103047478
Prohibitin.
   
 0.582
LOC103035142
Prohibitin.
   
 0.582
spg7
SPG7 matrix AAA peptidase subunit, paraplegin.
   
 
 0.556
Prkn
Parkin RBR E3 ubiquitin protein ligase.
    
 
 0.546
opa1
OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
 
 0.524
pgam5
PGAM family member 5, serine/threonine protein phosphatase, mitochondrial.
   
  
 0.524
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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