close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103041452AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa)    
Predicted Functional Partners:
ap1g1
AP-1 complex subunit gamma.
    
 0.982
ap1m2
AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
   
 0.978
LOC103044685
AP-1 complex subunit gamma.
    
 0.978
ap1m1
AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
    
 0.977
Ap1b1
AP complex subunit beta.
    
 0.976
LOC103032504
Adaptor related protein complex 1 subunit mu 3; Belongs to the adaptor complexes medium subunit family.
    
 0.971
ENSAMXP00000039227
Cyclin G associated kinase.
   
 
 0.940
LOC103023733
Adaptor related protein complex 1 subunit sigma 3b.
  
  
 
0.903
Ap1s3
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
  
  
 
0.901
W5L7F2_ASTMX
Uncharacterized protein.
     
  0.900
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (30%) [HD]