Xdh protein (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Xdh

Xanthine dehydrogenase. (1246 aa)

Predicted Functional Partners:

LOC103030682

0.959

LOC103041505

0.945

LOC103044190

0.944

LOC103033869

0.944

LOC111194529

0.944

tpmt

0.916

W5L332_ASTMX

0.901

LOC103021503

0.900

ENSAMXP00000042245

0.900

LOC103022041

0.900

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000042245	LOC103021503	ENSAMXP00000042245	ENSAMXP00000026829	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family.	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family.	0.901
ENSAMXP00000042245	LOC103022041	ENSAMXP00000042245	ENSAMXP00000053752	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family.	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family.	0.901
ENSAMXP00000042245	Xdh	ENSAMXP00000042245	ENSAMXP00000012142	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family.	Xanthine dehydrogenase.	0.900
LOC103021503	ENSAMXP00000042245	ENSAMXP00000026829	ENSAMXP00000042245	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family.	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family.	0.901
LOC103021503	LOC103022041	ENSAMXP00000026829	ENSAMXP00000053752	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family.	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family.	0.901
LOC103021503	Xdh	ENSAMXP00000026829	ENSAMXP00000012142	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family.	Xanthine dehydrogenase.	0.900
LOC103022041	ENSAMXP00000042245	ENSAMXP00000053752	ENSAMXP00000042245	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family.	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family.	0.901
LOC103022041	LOC103021503	ENSAMXP00000053752	ENSAMXP00000026829	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family.	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family.	0.901
LOC103022041	Xdh	ENSAMXP00000053752	ENSAMXP00000012142	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family.	Xanthine dehydrogenase.	0.900
LOC103030682	Xdh	ENSAMXP00000017891	ENSAMXP00000012142	Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family.	Xanthine dehydrogenase.	0.959
LOC103033869	LOC103041505	ENSAMXP00000021230	ENSAMXP00000014104	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.902
LOC103033869	LOC103044190	ENSAMXP00000021230	ENSAMXP00000008202	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.901
LOC103033869	LOC111194529	ENSAMXP00000021230	ENSAMXP00000027347	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	Purine nucleoside phosphorylase 5b.	0.901
LOC103033869	W5L332_ASTMX	ENSAMXP00000021230	ENSAMXP00000014244	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	Hypoxanthine phosphoribosyltransferase 1, like.	0.951
LOC103033869	Xdh	ENSAMXP00000021230	ENSAMXP00000012142	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	Xanthine dehydrogenase.	0.944
LOC103041505	LOC103033869	ENSAMXP00000014104	ENSAMXP00000021230	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.902
LOC103041505	LOC103044190	ENSAMXP00000014104	ENSAMXP00000008202	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.902
LOC103041505	LOC111194529	ENSAMXP00000014104	ENSAMXP00000027347	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	Purine nucleoside phosphorylase 5b.	0.902
LOC103041505	W5L332_ASTMX	ENSAMXP00000014104	ENSAMXP00000014244	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	Hypoxanthine phosphoribosyltransferase 1, like.	0.951
LOC103041505	Xdh	ENSAMXP00000014104	ENSAMXP00000012142	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	Xanthine dehydrogenase.	0.945