Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103036375TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (572 aa)    
Predicted Functional Partners:
Tradd
Tnfrsf1a-associated via death domain.
    
 0.994
tnfrsf1b
Tumor necrosis factor receptor superfamily, member 1B.
   
 0.991
W5LI45_ASTMX
Tumor necrosis factor receptor superfamily, member 1a.
    
 0.990
map3k1
Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase.
   
 0.987
map3k7
Mitogen-activated protein kinase kinase kinase 7.
   
 0.987
fadd
Fas (tnfrsf6)-associated via death domain.
   
 0.981
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.980
tab3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
    
 0.980
RIPK2
Receptor interacting serine/threonine kinase 2.
   
 0.980
LOC103038360
Si:ch211-1i11.3.
    
 0.979
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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