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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcaf7DDB1 and CUL4 associated factor 7. (342 aa)    
Predicted Functional Partners:
ENSAMXP00000052495
Damage-specific DNA binding protein 1.
    
 0.924
W5KKG9_ASTMX
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B.
   
 
 0.898
W5K5Y3_ASTMX
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b.
   
 
 0.874
Dyrk1a
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a.
   
 
 0.874
ercc8
Excision repair cross-complementation group 8.
     
 0.835
Dtl
Denticleless E3 ubiquitin protein ligase homolog (Drosophila).
     
 0.815
Cul4b
Cullin 4B; Belongs to the cullin family.
    
 0.788
Cul4a
Cullin 4A; Belongs to the cullin family.
    
 0.788
ENSAMXP00000048712
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.788
LOC103023991
Retinoblastoma binding protein 4, like.
     
 0.755
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.