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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)    
Predicted Functional Partners:
pik3ca
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.990
pik3cb
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
    
 0.986
pik3cd
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.983
gab1
GRB2-associated binding protein 1.
    
 0.976
LOC103032909
Zgc:158659; Belongs to the PI3/PI4-kinase family.
    
 0.975
irs1
Insulin receptor substrate 1.
    
 0.965
LOC103042975
Si:ch73-335l21.1.
    
 0.965
kdr
Kinase insert domain receptor (a type III receptor tyrosine kinase); Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.961
LOC103022926
3-phosphoinositide dependent protein kinase 1a.
     
 0.957
LOC103033547
3-phosphoinositide dependent protein kinase 1b.
     
 0.957
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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