Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
W5KXV1_ASTMXCrumbs cell polarity complex component 2b. (1012 aa)    
Predicted Functional Partners:
LOC103043088
Membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5); Belongs to the MAGUK family.
    
 0.768
mpp5
Membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5); Belongs to the MAGUK family.
    
 0.768
W5KU98_ASTMX
Erythrocyte membrane protein band 4.1 like 5.
    
 0.582
Prkci
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.446
ENSAMXP00000047304
Crumbs homolog 3b.
     
 0.437
Mybl2
V-myb avian myeloblastosis viral oncogene homolog-like 2b.
    
 
 0.436
NCSTN
Nicastrin.
    
 0.428
arid4a
AT rich interactive domain 4A (RBP1-like).
    
 0.419
W5K820_ASTMX
Translocase of outer mitochondrial membrane 20.
    
 0.419
Rbpjl
Recombination signal binding protein for immunoglobulin kappa J region-like.
    
 0.414
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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