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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rps6kc1Ribosomal protein S6 kinase polypeptide 1. (1033 aa)    
Predicted Functional Partners:
rint1
RAD50 interactor 1.
   
 0.977
use1
Unconventional SNARE in the ER 1 homolog (S. cerevisiae).
    
 0.976
Stx18
Syntaxin 18.
   
 0.973
zw10
Zw10 kinetochore protein.
    
 0.971
W5K3H8_ASTMX
Neuroblastoma amplified sequence.
   
 0.894
ENSAMXP00000036699
SEC22 homolog C, vesicle trafficking protein; Belongs to the synaptobrevin family.
   
 0.666
LOC103023153
SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family.
   
 0.666
Sec22a
SEC22 homolog A, vesicle trafficking protein; Belongs to the synaptobrevin family.
   
 0.666
katnal2
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
   
 
 0.645
kif11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
     
 0.631
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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