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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KYE2_ASTMXIntegrin beta; Belongs to the integrin beta chain family. (720 aa)    
Predicted Functional Partners:
itga5
Integrin, alpha 5 (fibronectin receptor, alpha polypeptide); Belongs to the integrin alpha chain family.
   
 0.972
ENSAMXP00000039033
Fibronectin 1b.
    
 0.967
itga6
Integrin, alpha 6a; Belongs to the integrin alpha chain family.
   
 0.956
ENSAMXP00000037794
Junctional adhesion molecule 2a.
     
 0.949
LOC103043894
Vitronectin a.
    
 0.948
vtn
Vitronectin b.
    
 0.947
itga2
Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2; Belongs to the integrin alpha chain family.
   
 0.946
Ptk2
Protein tyrosine kinase 2aa; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.946
tnr
Tenascin R (restrictin, janusin).
    
0.945
ENSAMXP00000029221
Uncharacterized protein.
    
0.945
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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