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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KYJ3_ASTMXGBD/FH3 domain-containing protein. (229 aa)    
Predicted Functional Partners:
LOC103040285
FH2 domain containing 4.
 
  
 
 0.854
LOC103027697
FH2 domain containing 3.
 
  
 
 0.840
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.756
W5LEY0_ASTMX
NPHS2 stomatin family member, podocin.
    
 
 0.580
ENSAMXP00000037764
NPHS1 adhesion molecule, nephrin.
     
 0.579
plce1
Phospholipase C, epsilon 1.
      
 0.577
zfyve21
Zinc finger, FYVE domain containing 21.
      
 0.577
actn4
Actinin, alpha 4.
      
 0.576
JMY
Junction mediating and regulatory protein, p53 cofactor.
   
 0.576
ENSAMXP00000033034
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
 0.516
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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