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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gata6GATA binding protein 6. (503 aa)    
Predicted Functional Partners:
LOC103025318
NK2 homeobox 5.
   
 0.858
nkx2-6
Homeobox domain-containing protein.
   
 0.771
zfpm2
Zinc finger protein, FOG family member 2a.
    
 0.766
lmo2
LIM domain only 2 (rhombotin-like 1).
    
 0.754
lmcd1
LIM and cysteine-rich domains 1.
    
 0.740
zfpm1
Zinc finger protein, FOG family member 1.
   
 0.719
Tal1
T-cell acute lymphocytic leukemia 1.
   
 0.685
LOC103026238
Zinc finger protein, FOG family member 2b.
    
 0.679
ENSAMXP00000039608
Forkhead box A1.
   
 0.660
hand2
Heart and neural crest derivatives expressed 2.
   
 0.638
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.