Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
slc2a6Solute carrier family 2 member 6; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (495 aa)    
Predicted Functional Partners:
rtraf
RNA transcription, translation and transport factor.
    
 0.647
slc22a16
Solute carrier family 22 member 16.
  
 
 0.617
Ap1b1
AP complex subunit beta.
    
  0.593
LOC103027662
Solute carrier family 38 member 4.
   
 
 0.593
ap2b1
AP complex subunit beta.
    
  0.593
cftr
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
    
 0.576
ddx1
DEAD (Asp-Glu-Ala-Asp) box helicase 1.
    
 0.570
ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
     
  0.557
il7r
Interleukin 7 receptor.
   
 
  0.540
Asmt
Acetylserotonin O-methyltransferase.
   
  
 0.538
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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