Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
W5KZ54_ASTMXSolute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (640 aa)    
Predicted Functional Partners:
b3gnt3
Hexosyltransferase.
      
 0.621
CCNO
Cyclin O; Belongs to the cyclin family.
      
 0.620
LOC103047478
Prohibitin.
    
 
 0.586
LOC103035142
Prohibitin.
    
 
 0.586
TIMM22
Translocase of inner mitochondrial membrane 22.
     
 0.555
timm10b
zf-Tim10_DDP domain-containing protein.
    
 
 0.543
timm13
Translocase of inner mitochondrial membrane 13 homolog (yeast); Belongs to the small Tim family.
     
 0.535
W5JY68_ASTMX
Cytochrome c oxidase subunit 6C.
    
   0.511
ndufa8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
      
 0.507
timm50
Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
      
 0.506
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.