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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
surf6Surfeit 6. (373 aa)    
Predicted Functional Partners:
ENSAMXP00000032529
Uncharacterized protein.
   
 
 0.950
mak16
Protein MAK16 homolog; Belongs to the MAK16 family.
   
   0.949
rpf1
Ribosome production factor 1 homolog.
   
 
 0.949
nifk
Nucleolar protein interacting with the FHA domain of MKI67.
   
 
 0.948
gtpbp4
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
   
 
 0.943
brix1
Brix domain containing 2.
   
 
 0.940
rrp15
Ribosomal RNA processing 15 homolog.
   
 
 0.939
W5LHZ2_ASTMX
EBNA1 binding protein 2.
   
 
 0.918
EBNA1BP2
EBNA1 binding protein 2.
   
 
 0.918
rsl1d1
Ribosomal L1 domain containing 1.
   
 
 0.910
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.