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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pak6Non-specific serine/threonine protein kinase. (699 aa)    
Predicted Functional Partners:
LOC103034468
Cell division cycle 42.
   
 0.973
LOC103045992
Rho guanine nucleotide exchange factor (GEF) 7a.
    
 0.966
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6.
    
 0.966
LOC103039613
Uncharacterized protein.
   
 0.966
LOC103036596
Rho guanine nucleotide exchange factor (GEF) 7b.
    
 0.966
LOC103038818
Cytoplasmic protein.
    
 0.961
nck2
Cytoplasmic protein.
    
 0.961
LOC103039384
LIM domain kinase 1b.
    
0.943
limk1
LIM domain kinase 1a.
    
0.943
W5KJM9_ASTMX
Uncharacterized protein.
    
 0.935
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.