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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103037241WW domain containing adaptor with coiled-coil a. (563 aa)    
Predicted Functional Partners:
ENSAMXP00000051962
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 
 0.941
W5LR04_ASTMX
RNA binding motif protein 25b.
   
 
 0.925
Cdc5l
CDC5 cell division cycle 5-like (S. pombe).
   
 
 0.870
sart1
Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP.
   
   0.826
sf3b3
Splicing factor 3b, subunit 3.
    
 
 0.825
sf3b2
Splicing factor 3b, subunit 2.
   
 
 0.825
Snrnp35
Small nuclear ribonucleoprotein 35 (U11/U12).
    
 
 0.808
snrnp70
RRM domain-containing protein.
    
 
 0.808
ddx46
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.
   
 
 0.790
rnf40
E3 ubiquitin protein ligase.
   
 0.785
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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