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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
klhl17Kelch-like family member 17. (591 aa)    
Predicted Functional Partners:
W5KW74_ASTMX
Sequestosome 1.
    
 0.854
W5KX87_ASTMX
Cullin 3a; Belongs to the cullin family.
    
 0.827
cul3
Cullin 3b; Belongs to the cullin family.
    
 0.827
Rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.801
nfe2l2
Nuclear factor, erythroid 2-like 2a.
    
 0.789
LOC103040845
Nuclear factor, erythroid 2-like 2b.
    
 0.789
bbs1
Bardet-Biedl syndrome 1.
    
 0.711
LOC103038537
Nuclear factor, erythroid 2-like 1a.
    
 0.688
NFE2L1
Nuclear factor, erythroid 2 like 1.
    
 0.688
bbs9
Bardet-Biedl syndrome 9.
    
 0.684
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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