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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pggt1bProtein geranylgeranyltransferase type I, beta subunit. (362 aa)    
Predicted Functional Partners:
fnta
Farnesyltransferase, CAAX box, alpha.
    
 0.998
gart
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
      
 0.692
icmt
Protein-S-isoprenylcysteine O-methyltransferase.
      
 0.565
zmpste24
CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.
      
 0.499
W5LG45_ASTMX
Sorting and assembly machinery component 50 homolog, like.
      
 0.438
ENSAMXP00000027492
SAMM50 sorting and assembly machinery component.
      
 0.438
ppp5c
Serine/threonine-protein phosphatase.
      
 0.436
rabggta
Rab geranylgeranyltransferase subunit alpha.
      
 0.426
LOC103028746
Ras converting CAAX endopeptidase 1b.
      
 0.420
rce1
Ras converting CAAX endopeptidase 1a.
      
 0.420
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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