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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5L0T6_ASTMXInhibitor of nuclear factor kappa B kinase subunit beta. (708 aa)    
Predicted Functional Partners:
W5LI45_ASTMX
Tumor necrosis factor receptor superfamily, member 1a.
   
 0.966
LOC103041009
Tumor necrosis factor b (TNF superfamily, member 2).
   
 0.957
LOC103038271
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a.
    
 0.951
nfkbia
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b.
    
 0.951
map3k7
Mitogen-activated protein kinase kinase kinase 7.
   
0.924
optn
Optineurin.
    
 0.918
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.883
ikbkg
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
   
 0.882
LOC103027564
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta.
    
 0.877
W5KCM9_ASTMX
Mitogen-activated protein kinase kinase kinase 14a.
   
0.875
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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