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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5L1E4_ASTMXAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (744 aa)    
Predicted Functional Partners:
tmem208
Transmembrane protein 208.
    
   0.860
Becn1
Beclin 1, autophagy related.
    
 0.860
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.831
pik3r4
Phosphoinositide-3-kinase, regulatory subunit 4.
     
 0.829
W5JYH4_ASTMX
Unc-51 like autophagy activating kinase 1a.
   
 
 0.826
ulk1
Unc-51 like autophagy activating kinase 1.
   
 
 0.826
ulk2
Unc-51 like autophagy activating kinase 2.
   
 
 0.826
ATG14
Autophagy related 14.
     
 0.789
wipi1
WD repeat domain, phosphoinositide interacting 1.
   
 
 0.745
wipi2
WD repeat domain, phosphoinositide interacting 2.
   
 
 0.727
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.