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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpp1Tripeptidyl peptidase I. (558 aa)    
Predicted Functional Partners:
pot1
Protection of telomeres 1 homolog.
    
 0.776
ENSAMXP00000045230
TERF1 (TRF1)-interacting nuclear factor 2.
    
 0.719
terf1
Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
    
 0.700
ppt1
Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile).
   
  
 0.663
W5K9C2_ASTMX
Uncharacterized protein.
    
 0.601
cln3
Battenin.
      
 0.578
cln5
CLN5 intracellular trafficking protein.
      
 0.577
mfsd8
Major facilitator superfamily domain containing 8.
      
 0.567
cln8
CLN8 transmembrane ER and ERGIC protein.
    
 0.562
W5L434_ASTMX
CTS telomere maintenance complex component 1.
    
 0.508
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.