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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5L1U6_ASTMXProtein tyrosine phosphatase receptor type Eb. (582 aa)    
Predicted Functional Partners:
W5KW72_ASTMX
Uncharacterized protein.
    
 0.695
LOC103046713
Growth factor receptor-bound protein 2a.
   
 0.693
LOC103046713-2
Growth factor receptor-bound protein 2-like.
   
 0.693
LOC111191028
Growth factor receptor-bound protein 2b.
   
 0.693
ENSAMXP00000052634
Uncharacterized protein.
    
 0.616
slitrk2
SLIT and NTRK-like family, member 2.
    
 0.590
LOC103047695
Interleukin 1 receptor accessory protein-like 1a.
   
 0.581
Il1rapl1
Interleukin 1 receptor accessory protein-like 1b.
   
 0.581
LOC103028306
Leucine rich repeat and fibronectin type III domain containing 5a.
    
 0.556
LOC103029737
Leucine rich repeat and fibronectin type III domain containing 5b.
    
 0.556
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.