hlx protein (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

hlx

H2.0-like homeo box 1 (Drosophila). (374 aa)

Predicted Functional Partners:

Nup160

0.712

rpl13a

0.624

arhgef2

0.610

znf148

0.555

LOC103043802

0.545

LOC103030146

0.545

LOC103042449

0.492

esrrb

0.492

ENSAMXP00000033913

0.492

Tbx21

0.481

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000033913	hlx	ENSAMXP00000033913	ENSAMXP00000013823	Estrogen-related receptor gamma a.	H2.0-like homeo box 1 (Drosophila).	0.492
LOC103030146	arhgef2	ENSAMXP00000037713	ENSAMXP00000004707	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Rho/rac guanine nucleotide exchange factor (GEF) 2.	0.632
LOC103030146	hlx	ENSAMXP00000037713	ENSAMXP00000013823	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	H2.0-like homeo box 1 (Drosophila).	0.545
LOC103030146	znf148	ENSAMXP00000037713	ENSAMXP00000053097	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Zinc finger protein 148.	0.594
LOC103042449	hlx	ENSAMXP00000001680	ENSAMXP00000013823	Estrogen-related receptor gamma b.	H2.0-like homeo box 1 (Drosophila).	0.492
LOC103043802	arhgef2	ENSAMXP00000016779	ENSAMXP00000004707	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Rho/rac guanine nucleotide exchange factor (GEF) 2.	0.632
LOC103043802	hlx	ENSAMXP00000016779	ENSAMXP00000013823	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	H2.0-like homeo box 1 (Drosophila).	0.545
LOC103043802	znf148	ENSAMXP00000016779	ENSAMXP00000053097	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Zinc finger protein 148.	0.594
Nup160	hlx	ENSAMXP00000046766	ENSAMXP00000013823	Nucleoporin 160.	H2.0-like homeo box 1 (Drosophila).	0.712
Tbx21	hlx	ENSAMXP00000010803	ENSAMXP00000013823	T-box transcription factor 21.	H2.0-like homeo box 1 (Drosophila).	0.481
arhgef2	LOC103030146	ENSAMXP00000004707	ENSAMXP00000037713	Rho/rac guanine nucleotide exchange factor (GEF) 2.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.632
arhgef2	LOC103043802	ENSAMXP00000004707	ENSAMXP00000016779	Rho/rac guanine nucleotide exchange factor (GEF) 2.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.632
arhgef2	hlx	ENSAMXP00000004707	ENSAMXP00000013823	Rho/rac guanine nucleotide exchange factor (GEF) 2.	H2.0-like homeo box 1 (Drosophila).	0.610
arhgef2	rpl13a	ENSAMXP00000004707	ENSAMXP00000049104	Rho/rac guanine nucleotide exchange factor (GEF) 2.	Ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family.	0.402
arhgef2	znf148	ENSAMXP00000004707	ENSAMXP00000053097	Rho/rac guanine nucleotide exchange factor (GEF) 2.	Zinc finger protein 148.	0.536
esrrb	hlx	ENSAMXP00000031106	ENSAMXP00000013823	Estrogen-related receptor beta.	H2.0-like homeo box 1 (Drosophila).	0.492
hlx	ENSAMXP00000033913	ENSAMXP00000013823	ENSAMXP00000033913	H2.0-like homeo box 1 (Drosophila).	Estrogen-related receptor gamma a.	0.492
hlx	LOC103030146	ENSAMXP00000013823	ENSAMXP00000037713	H2.0-like homeo box 1 (Drosophila).	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.545
hlx	LOC103042449	ENSAMXP00000013823	ENSAMXP00000001680	H2.0-like homeo box 1 (Drosophila).	Estrogen-related receptor gamma b.	0.492
hlx	LOC103043802	ENSAMXP00000013823	ENSAMXP00000016779	H2.0-like homeo box 1 (Drosophila).	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.545