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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNK12Potassium two pore domain channel subfamily K member 12; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (406 aa)    
Predicted Functional Partners:
erlec1
Endoplasmic reticulum lectin 1.
      
 0.726
Kcnk18
Uncharacterized protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.621
msh2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
      
 0.604
KCNK4
Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.582
LOC103042783
Potassium channel, subfamily K, member 4a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.582
Psme4
Proteasome activator subunit 4b.
      
 0.567
KCNK16
Potassium two pore domain channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.527
FBXO11
F-box protein 11a.
      
 0.519
fbxo11
F-box protein 11a.
      
 0.519
kcnk5
Potassium channel, subfamily K, member 5a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.499
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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