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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ticrrTreslin_N domain-containing protein. (1798 aa)    
Predicted Functional Partners:
topbp1
DNA topoisomerase II binding protein 1.
    
 
 0.911
Fbl
Fibrillarin.
   
 
 0.911
tbl3
Transducin (beta)-like 3.
   
 
 0.813
wdr36
WD repeat domain 36.
   
 
 0.807
W5KFH6_ASTMX
CDC45 cell division cycle 45 homolog (S. cerevisiae).
   
  
 0.801
exo1
Exonuclease 1.
  
 
 0.800
LOC103032036
PWP2 small subunit processome component.
   
 
 0.790
utp4
UTP4 small subunit processome component.
   
 
 0.789
utp15
UTP15 small subunit processome component.
   
 
 0.783
utp6
UTP6 small subunit processome component.
   
 
 0.771
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.