close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppp1r42Protein phosphatase 1, regulatory subunit 42. (338 aa)    
Predicted Functional Partners:
cops4
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis).
   
 0.982
COPS6
COP9 signalosome subunit 6.
   
 0.981
cops2
COP9 signalosome subunit 2.
   
 0.980
cops3
COP9 signalosome subunit 3.
   
 0.978
cops8
COP9 signalosome subunit 8.
   
 0.977
gps1
G protein pathway suppressor 1.
   
 0.976
cops7a
COP9 constitutive photomorphogenic homolog subunit 7A.
    
 0.974
fau
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.938
cul2
Cullin 2; Belongs to the cullin family.
   
 0.937
LOC103040682
NEDD8 ubiquitin like modifier.
   
 0.926
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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