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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UPF2UPF2 regulator of nonsense mediated mRNA decay. (1288 aa)    
Predicted Functional Partners:
upf1
UPF1 RNA helicase and ATPase.
   
 0.999
upf3a
UPF3A regulator of nonsense mediated mRNA decay.
   
 0.997
rbm8a
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
    
 0.989
W5JXZ5_ASTMX
UPF3B regulator of nonsense mediated mRNA decay.
   
 0.981
Smg1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.
   
 
 0.975
LOC103024569
RRM domain-containing protein.
    
 0.972
Rnps1
RNA binding protein S1, serine-rich domain.
    
 0.972
Srrm1
PWI domain-containing protein.
    
 
 0.954
casc3
Casc3 exon junction complex subunit.
    
 0.915
Ncmap
Si:dkey-221l4.10.
    
 
 0.909
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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