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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103033109Ras association domain family member 1. (356 aa)    
Predicted Functional Partners:
sav1
Salvador family WW domain containing protein 1.
    
 
 0.704
rassf5
Ras association domain family member 5.
  
 
 
0.702
daxx
Death-domain associated protein.
    
 
 0.682
STK4
Serine/threonine kinase 4.
    
 0.680
stk3
Serine/threonine kinase 3 (STE20 homolog, yeast).
    
 0.680
nprl2
NPR2 like, GATOR1 complex subunit.
      
 0.532
rasl11b
RAS-like, family 11, member B.
    
 
 0.516
LOC107196922
Microtubule associated tumor suppressor 1b.
    
 0.491
ENSAMXP00000041860
Microtubule associated tumor suppressor 1a.
    
 0.491
Mdm2
MDM2 proto-oncogene.
   
 
 0.476
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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