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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bap1Ubiquitin carboxyl-terminal hydrolase. (768 aa)    
Predicted Functional Partners:
psmd4
Proteasome 26S subunit, non-ATPase 4a.
    
 0.995
Asxl2
ASXL transcriptional regulator 2.
    
 0.994
adrm1
Adhesion regulating molecule 1.
   
 0.976
psmd14
Proteasome 26S subunit, non-ATPase 14.
   
 0.975
psmd8
Proteasome 26S subunit, non-ATPase 8.
   
 0.975
bard1
BRCA1 associated RING domain 1.
    
 0.974
psmd7
Proteasome 26S subunit, non-ATPase 7.
   
 0.966
psma1
Proteasome subunit alpha type.
   
 0.965
psmc4
Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.
   
 0.965
Psmd2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
 0.964
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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