Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
e2f3Transcription factor E2F3. (416 aa)    
Predicted Functional Partners:
rb1
Retinoblastoma-associated protein.
   
 0.991
rbl1
Retinoblastoma-like protein 1.
   
 0.981
ccna2
cyclin-A2; Belongs to the cyclin family.
   
 0.981
rbl2
Retinoblastoma-like protein 2 isoform X3.
   
 0.981
ccna1
cyclin-A1 isoform X2; Belongs to the cyclin family.
   
 0.974
cdk2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
    
 0.967
tfdp1
Transcription factor.
   
 0.955
LOC108277808
Transcription factor.
   
 0.955
LOC108266453
Transcription factor.
   
 0.955
ENSIPUP00000037178
annotation not available
   
 0.787
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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