Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC108267420Insulin receptor substrate 2-B-like. (1178 aa)    
Predicted Functional Partners:
LOC108256494
Growth factor receptor-bound protein 2.
    
 0.976
grb2
Growth factor receptor-bound protein 2 isoform X1.
    
 0.976
LOC108267827
Tyrosine-protein kinase receptor.
    
 0.972
LOC108271091
Tyrosine-protein kinase receptor.
    
 0.971
igf1r
Tyrosine-protein kinase receptor.
    
 0.971
socs3
Suppressor of cytokine signaling 3.
    
 0.955
mtor
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
 0.955
LOC108274104
Suppressor of cytokine signaling 3-like.
    
 0.936
ikbkb
Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.
    
 0.928
chuk
Inhibitor of Nuclear factor kappa-B kinase subunit alpha.
    
 0.924
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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