Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cxcr5C-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (361 aa)    
Predicted Functional Partners:
cxcl13
Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family.
     
 0.940
cd44
CD44 antigen.
     
 0.907
LOC108259084
Uncharacterized protein LOC108259084.
   
  
 0.863
cxcl12
Stromal cell-derived factor 1 precursor; Belongs to the intercrine alpha (chemokine CxC) family.
    
 0.780
LOC108255518
C-C motif chemokine 19-like isoform X1.
    
 0.751
cd40lg
CD40 ligand; Belongs to the tumor necrosis factor family.
   
  
 0.741
LOC108255519
C-C motif chemokine.
   
 0.721
batf
Basic leucine zipper transcriptional factor ATF-like.
      
 0.710
LOC100415908
CD8 alpha precursor.
      
 0.699
rag1
V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]
      
 0.691
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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