Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC108279496Cleavage and polyadenylation specificity factor subunit 6-like isoform X1. (120 aa)    
Predicted Functional Partners:
cpsf6
Cleavage and polyadenylation specificity factor subunit 6 isoform X2.
 
   
  0.979
nudt21
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
   
 0.949
tnpo3
Transportin-3.
   
 0.941
cpsf7
Cleavage and polyadenylation specificity factor subunit 7 isoform X1.
 
   
  0.914
pcf11
pre-mRNA cleavage complex 2 protein Pcf11.
    
 0.868
cstf2
Cleavage stimulation factor subunit 2 isoform X1.
   
 0.842
rbbp6
E3 ubiquitin-protein ligase RBBP6 isoform X1.
    
 0.781
cpsf3
Cleavage and polyadenylation specificity factor subunit 3.
   
 0.778
cpsf2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.756
cstf3
Cleavage stimulation factor subunit 3.
   
 0.755
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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