Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
LOC108266232Guanine nucleotide exchange factor DBS-like isoform X1. (823 aa)    
Predicted Functional Partners:
cdc42
Cell division control protein 42-like protein.
    
 0.700
LOC108276251
Cell division control protein 42 homolog.
    
 0.700
LOC108272678
Cell division control protein 42 homolog.
    
 0.621
rhoc
Rho-related gtp-binding protein rhoc.
    
 0.523
LOC108265880
Rho-related GTP-binding protein RhoA-B.
    
 0.523
RHOB
Rho-related GTP-binding protein RhoB.
    
 0.523
LOC108275781
Rho-related GTP-binding protein RhoA-C.
    
 0.523
LOC108265463
Rho-related GTP-binding protein RhoA-A.
    
 0.523
LOC108254710
Transforming protein RhoA-like.
    
 0.523
LOC108271788
Rho-related GTP-binding protein RhoA-D-like.
    
 0.523
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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