Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
xrcc6X-ray repair cross-complementing protein 6. (609 aa)    
Predicted Functional Partners:
xrcc5
X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.
   
 0.999
prkdc
DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family.
   
 0.998
lig4
DNA ligase.
   
 0.995
wrn
Werner syndrome ATP-dependent helicase isoform X1.
   
 
 0.989
LOC108279967
Protein artemis-like isoform X2.
   
 0.989
lig3
DNA ligase.
   
 0.989
rad50
DNA repair protein RAD50 isoform X1.
   
 0.987
parp1
Poly [ADP-ribose] polymerase.
   
 
 0.985
aplf
Aprataxin and PNK-like factor isoform X4.
    
 
 0.984
bax
Apoptosis regulator BAX.
    
 
 0.980
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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