Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
htr3b5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (392 aa)    
Predicted Functional Partners:
HTR7
5-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family.
      
 0.746
LOC108269542
5-hydroxytryptamine receptor 1D-like.
      
 0.615
LOC108258316
5-hydroxytryptamine receptor 3A-like isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
    
 0.493
LOC108270621
5-hydroxytryptamine receptor 3A-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
    
 0.493
htr1b
5-hydroxytryptamine receptor 1B.
      
 0.483
HTR1B
5-hydroxytryptamine receptor 1B-like.
      
 0.483
LOC108268830
Pro-neuregulin-2, membrane-bound isoform-like isoform X1.
   
 0.415
nrg2
Pro-neuregulin-2, membrane-bound isoform isoform X4.
   
 0.415
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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