Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC108262534ER lumen protein-retaining receptor. (200 aa)    
Predicted Functional Partners:
tmed10
Transmembrane emp24 domain-containing protein 10.
   
 0.879
copb1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 0.829
LOC100304967
Surfeit locus protein 4.
   
 0.798
surf4
Surfeit locus protein 4.
   
 0.798
trip12
E3 ubiquitin-protein ligase TRIP12.
    
   0.779
arfgap1
ADP-ribosylation factor GTPase-activating protein 1 isoform X1.
    
 0.756
gbf1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform X1.
    
 0.726
ykt6
Synaptobrevin homolog YKT6; Belongs to the synaptobrevin family.
   
 
 0.720
LOC108279806
Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 
 0.719
LOC108277309
Transmembrane emp24 domain-containing protein 2-like.
   
 0.718
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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