Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sox10Transcription factor SOX-10. (468 aa)    
Predicted Functional Partners:
foxd3
Forkhead box protein D3.
    
 0.957
olig2
Oligodendrocyte transcription factor 2.
   
 
 0.912
mitf
Microphthalmia-associated transcription factor isoform X1.
    
 0.860
LOC108280216
Paired box protein Pax-3-like isoform X2.
   
 0.860
LOC108260967
5,6-dihydroxyindole-2-carboxylic acid oxidase-like.
    
 0.782
runx2
Runt-related transcription factor.
   
 0.780
dct
L-dopachrome tautomerase.
    
 0.760
tfap2a
Transcription factor AP-2-alpha isoform X3.
   
 
 0.759
olig1
Oligodendrocyte transcription factor 1.
   
 
 0.758
ctnnb1
Catenin beta-1 isoform X3.
    
 0.732
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.